More than 5500 Canberrans braved the cold weather yesterday to take in the 15th Mother's Day Classic.

They joined more than 125,000 Australians across the country by running or walking around Lake Burley Griffin to raise money for breast cancer research.

The event took place in 53 Australian cities and towns and organisers hope to raise $4.2 million.

One of the runners in Canberra was ACT Chief Minister Katy Gallagher, who ran the five kilometre event.

Before each race a minute's silence was held in memory of the women who have lost their battle with the deadly disease.

National manager of the Mother's Day Classic Sharon Morris said the ACT had the highest rate of breast cancer in the nation and across the country it is the most common cancer among women.