Kidney disease has affected one in 10 Australians in the past year, while one in three was at risk of coming down with the condition.

To raise awareness of her husband's illness and raise money for research into a cure, Mrs Moloney said she decided to organise Canberra's second Big Red Kidney Walk.

"I can't do anything for my husband, I can't change the situation he's in. There are 16,000 people waiting for a kidney and are on dialysis," she said.

"So I'm thinking, I only have one kidney I can donate, I have three kids in the future who could have the same issue, what can I do to make people aware?"

Up to 2000 people are expected to attend the event, which will start at the Carillon on Lake Burley Griffin at 11am on Sunday.

Already $120,000 has been raised in 2014 at walks around Australia and Mrs Moloney said she would love to add another $20,000 to the total.

"I just want people to come down on the day," she said. "They don't have to do the walk, they can just get information about their kidneys and other health information."

Organising committee member Kathryn Tucker said kidney health affected many Canberrans, many of whom did not know they were ill until it was too late.

"They think it's an old people's condition and it's something you can have very few symptoms of until it is too late," she said.

"We just want people to be aware and get more awareness of it now, so they can keep an eye on it, keep checking it and if there is any problem with them they can get on it early rather than later, because it can be devastating."