Melbourne's contentious strategy of seeking to revive the career of other clubs' fringe players has got off to a bad start, with two of those recruits dumped after just one match.
Midfielder David Rodan and key-position utility Cameron Pedersen were axed by coach Mark Neeld after the Demons' 79-point thrashing by Port Adelaide last week, as was flanker Luke Tapscott.
The trio, and the injured Lynden Dunn, have been replaced for Saturday night's match against Essendon by Jack Trengove, Tom McDonald, Aaron Davey and Dean Terlich.
The Bombers have named an unchanged team.
Collingwood could blood its fourth debutant in just its second match following its promotion of dashing forward Ben Kennedy to its extended interchange bench for Sunday's match against Carlton.
Key forward Sam Rowe is guaranteed to debut for Carlton and could be joined by 20-year-old Dylan Buckley. Tom Bell will return and Jeremy Laidler was named in the squad by the Blues, who left out Aaron Joseph and injured pair Eddie Betts and Shaun Hampson.
The loss of Jared Rivers (knee) for Geelong was offset by the inclusions of James Kelly and Joel Corey for its match against North Melbourne.
The Kangaroos recalled Scott McMahon and included Majak Daw for a possible debut.