Brisbane will send almost half of their 2013 AFL playing list to Arizona for pre-season altitude training.
The Lions on Thursday announced an experienced group of 18 players, all of which have had at least five AFL seasons, would leave for the United States on November 7 for a two-and-a-half week camp.
Unlike most clubs, who have taken all or most of their squads to the US for high-altitude training, Brisbane sent a small group of five senior players to Arizona at the end of last year.
The club's physical performance manager, Brett Burton, said the experience of the 2011 camp was a key factor in returning.
"The objectives out of last year's camp were to provide a new stimulus for the players, and to deload the muscular-skeletal system - which basically means less of a load on their bodies with the same conditioning benefit, and we achieved both of those objectives," Burton said in a Lions statement.
"With the conditioning benefits of altitude training, along with having that new training environment, we're confident that we'll get some good results for our guys out of this year's camp."
Brisbane were a quiet improver in 2012, finishing 13th on the AFL ladder with 10 wins - six more than 2011.