ACT Health officials have expressed concern about methadone overdoses and mistakes with anti-depressant medication at the Alexander Maconochie Centre.
Documents issued under Freedom of Information laws cite eight incidents within a six-week period at the jail in October and November.
They include multiple methadone overdoses and an inmate going six days without receiving prescribed lithium.
But an ACT Health spokesman said there had only been seven incidents since the jail began operating last March.
A former prisoner at the jail has also said a daily methadone dose was not given on the prisoner's last day in the jail in November.
The prisoner had to go to the Canberra Hospital for an emergency dose of the anti-addictive medication.
In emails sent last November, clinical risk coordinator Sharon Swain raised the issue of ''eight medication-related incidents''.
''We have a level of concern regarding a number of them [medication incidents] and have debated whether these should be reported as high risk incidents, specifically the methadone overdoses.''
There are 48 inmates at the centre currently taking part in a methadone program.
The emails also refer to an ''amitryptiline incident'' occurring at the prison. The drug is used for the treatment of depression.
In responses to questions, an ACT Health spokesman said the incidents did not lead to any ''adverse health outcomes''.
He said the ''incidents will be referred for review by the Clinical Review Committee to identify any systemic issues for improvement''.
''From time to time in all health facilities there are issues in relation to the administration of medication.''
Summaries and reports of the incidents detailing their exact nature and date were not given to The Canberra Times, to protect the privacy of the patients.
The incidents follow the death of Andreas Bulig in his cell at the Alexander Maconochie Centre on August 12 last year. The 44-year-old had applied for bail weeks before his death citing a lack of access to epilepsy medication.
Bulig believed to have been a long-term injecting drug user had a seizure three days before his death, but was given a clean bill of health and released back to his cell on August 10. A coronial inquest into his death is expected later this year.
Opposition corrections spokesman Jeremy Hanson said the incidents needed to be investigated to avoid further problems, including risks to the safety of other inmates and corrections officers.