A female cyclist, believed to be the owner of a prominent vineyard, has died after colliding with a ute on Cassilis Road in Mudgee.

Police were called to Cassilis Road about 8am on Sunday after reports of a collision between a cyclist and a Ford ute. The woman, 57, died at the scene.

The driver, a 33-year-old man, was unharmed but taken to Mudgee Hospital for mandatory blood and urine testing.