Glasgow Warriors prop Ryan Grant will play his first Test among six changes in Scotland's team named Saturday to play Australia in Newcastle on Tuesday.
Apart from Grant, 26, there will be a first start for Edinburgh's 21-year-old centre Matt Scott while two other uncapped players, Edinburgh wing/fullback Tom Brown and Glasgow lock Tom Ryder, were named among the replacements.
Omitted from the team that lost 13-6 to Italy in Rome in the Six Nations in March were Jon Welsh, Geoff Cross, Jim Hamilton and David Denton in the pack and Max Evans and Graeme Morrison among the backs.
They were replaced by Grant, Euan Murray, Al Kellock, Alasdair Strokosch, Joe Ansbro and Scott respectively.
In a positional switch John Barclay will move from blindside flank to number eight.
Some of the changes were enforced with Denton ruled out through injury, while Evans was with his club in France.
Head coach Andy Robinson said the selection was based around a desire to improve Scotland's fortunes after finishing with the wooden spoon in this year's Six Nations.
"We were all very disappointed by the results in the Six Nations and this tour is about our strong collective determination to put that right, play with confidence and win back pride," Robinson said.
"There's been an intensity to training since we've been out here which has pleased me but, as ever, it's about delivering a consistent 80 minute performance and eliminating the sort of errors that have cost us dearly if we are to beat Australia."
Scotland (15-1): Stuart Hogg (Glasgow); Joe Ansbro (London Irish/ENG), Nick De Luca (Edinburgh), Matt Scott (Edinburgh), Sean Lamont (Scarlets/WAL); Greig Laidlaw (Edinburgh), Mike Blair (Edinburgh); Ryan Grant (Glasgow), Ross Ford (Edinburgh, capt), Euan Murray (Newcastle/ENG); Alastair Kellock (Glasgow), Richie Gray (Glasgow); Alasdair Strokosch (Gloucester/ENG), Ross Rennie (Edinburgh), John Barclay (Glasgow).