A 42-year-old Horsham man has been killed in a two-car collision at Pimpinio in the state's west on Monday afternoon.
The collision happened at the intersection of Quantong-Cemetery and Polkemmet roads at about 4.30pm.
Police believe the crash occurred when one of the vehicles, which was travelling north on Quantong-Cemetery Road, collided with a car travelling east on Polkemmet Road.
The driver of the east-bound car died at the scene while the driver of the other vehicle, a man in his late 60s, was rushed to the Wimmera Base Hospital with only minor injuries.
Investigators believe that several drivers stopped at the collision scene and are appealing for them to contact Crime Stoppers on 1800 333 000 or visit www.crimestoppers.com.au.
The death brings Victoria's road toll for the year to 95.