Two hundred people were arrested today at the Creamfields dance music festival in a police crackdown on drugs and drinking.

Officers worked with Passive Alert Detection (PAD) sniffer dogs to detect illicit substances at the Melbourne Showgrounds event in Flemington.

Police apprehended 180 men and 20 women for drug and drinking offences.

Drugs seized included ecstasy, cocaine, cannabis and amphetamines.

Of those arrested, 175 were referred to a drug diversion program.

Acting Senior Sergeant Mark Pilkington said police were disappointed people continued to bring illicit drugs to these types of events.

“These drugs are dangerous, they are manufactured by criminals with no regard for peoples' safety.

“We will continue to police these types of events in an attempt to limit the impact these drugs have on society," he said.

Ambulance Victoria spokesman Ray Rowe said one male had been taken to the Royal Melbourne Hospital in Parkville with a suspected drug overdose.

"He is now in a stable condition," Mr Rowe said.

The blitz was one of the biggest at a Melbourne music festival.

In March, police arrested 45 people for drug offences at the Future Music Festival, while in January 20 people were arrested at the Big Day Out, both held at the Flemington racecourse.

In December, there were 89 arrests for possession of a drug of dependence at the Stereosonic festival, also at the Melbourne Showgrounds.