Israeli police officers examine the destroyed bus at the site of the bombing in Tel Aviv.

Aftermath ... Police officers examine the destroyed bus at the site of the bombing in Tel Aviv. Photo: AP

A BLAST on a Tel Aviv bus that injured at least 10 people on Wednesday, three of them seriously, was ''a terrorist attack'', the Israeli Prime Minister's spokesman said.

The bus exploded about noon on one of the coastal city's busiest arteries, near the Tel Aviv museum and across from an entrance to the Kirya, Israel's national defence headquarters.

''A bomb exploded on a bus in central Tel Aviv. This was a terrorist attack,'' Prime Minister Benjamin Netanyahu's spokesman, Ofir Gendelman, said on his official Twitter account.

Medics said at least 10 people were wounded, three seriously.

The bus was charred and blackened, its side windows blown out and its glass scattered on the asphalt.

An Israeli driver who witnessed the explosion told Israel's Army Radio the bus was ''completely charred inside''.

Another witness said there were few passengers on the bus when it exploded.

A police spokesman, Micky Rosenfeld, said authorities were investigating whether the bomb had been planted and left on the bus or whether it was the work of a suicide bomber.

The bombing came amid a week-long Israeli offensive against Palestinian militants in Gaza that has killed more than 130 Palestinians.

Rocket fire into Israel has killed five Israelis.

❏ An office of Arab satellite broadcaster Al-Jazeera in Cairo, Egypt, has been firebombed as protesters clashed near the downtown Tahrir Square.

''Unknown assailants'' lobbed petrol bombs at the office, ''causing a big fire which rescue services are working to put out,'' the official said.

Agence France-Presse