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Washington: US President Barack Obama urged Russia on Sunday to stop bombing "moderate" rebels in Syria in support of its ally Bashar al-Assad, a campaign seen in the West as a major obstacle to latest efforts to end the war.
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US Senator John McCain says Russia's role in Syria is holding the destablized, conflict-ridden country back from achieving peace.
Major powers agreed on Friday to a limited cessation of hostilities in Syria but the deal does not take effect until the end of this week and was not signed by any warring parties – the Damascus government and numerous rebel factions fighting it.
Russian bombing raids directed at rebel groups are meanwhile helping the Syrian army to achieve what could be its biggest victory of the war in the battle for Aleppo, the country's largest city and commercial hub before the conflict.
The Kremlin said President Vladimir Putin and Mr Obama had agreed to intensify cooperation to implement the agreement on Syria struck in Munich.
After a phone call between Mr Putin and Mr Obama, the Kremlin said both gave a "positive valuation" to the Munich meeting.
The Kremlin statement made clear Russia was committed to its campaign against Islamic State and "other terroristic organisations", an indication that it would also be targeting groups in western Syria where jihadists such as al-Qaeda are fighting Mr Assad in close proximity to rebels deemed moderate by the West.
Russia says the "cessation" does not apply to its air strikes, which have shifted the balance of power towards Assad.
It says Islamic State and the al Qaeda-affiliated Nusra Front are the main targets of its air campaign, but Western countries say Russia has in fact been mostly targeting other insurgent groups, including some they support.
The White House said Mr Obama's discussion with Mr Putin stressed the need to rush humanitarian aid to Syria and contain air strikes.
"In particular, President Obama emphasised the importance now of Russia playing a constructive role by ceasing its air campaign against moderate opposition forces in Syria," the White House said in a statement.
Relief workers said efforts to deliver humanitarian aid were being threatened by the latest escalation of violence.
"We must ask again, why wait a week for this urgently needed cessation of hostilities?" said Dalia al-Awqati, Mercy Corps Director of Programs for North Syria.
The situation in Syria has been complicated by the involvement of Kurdish-backed combatants in the area north of Aleppo near the Turkish border, which has drawn a swift military response from artillery in Turkey.
The Kurdish YPG militia, helped by Russian air raids, seized an ex-military air base at Menagh last week, angering Turkey, which sees the YPG as an extension of the PKK, a Kurdish group that waged a bloody insurgent campaign on Turkish soil over most of the past three decades.
Turkey began shelling while demanding that the YPG militia withdraw from areas it has captured from Syrian rebels in the northern Aleppo region in recent days, including the Menagh air base. The bombardment killed two YPG fighters, according to the Syrian Observatory for Human Rights.
The Syrian Kurdish PYD party rejected Turkish demands for withdrawal, while the Syrian government said Turkish shelling of northern Syria amounted to direct support for insurgent groups.
Other fronts were also active on Sunday.
Kurdish-backed forces were fighting with insurgent groups near Tel Rifaat in the northern Aleppo countryside, while further south, government forces renewed their shelling of rebel positions to the northwest of Aleppo city.
The Observatory also reported air strikes by jets believed to be Russian in areas east of Damascus, north of Homs, and in the southern province of Deraa.
'Mr Putin is not interested in being our partner'
Reaction from politicians in the West to the Munich deal was sceptical.
US Senator John McCain said he did not view the deal as a breakthrough.
"Let's be clear about what this agreement does. It allows Russia's assault on Aleppo to continue for another week," he said at security conference in Munich," he said.
"Mr Putin is not interested in being our partner. He wants to shore up the Assad regime, he wants to establish Russia as a major power in the Middle East, he wants to use Syria as a live fire exercise for Russia's modernising military."
A senior ally of German Chancellor Angela Merkel said Russia had gained the upper hand in Syria and the surrounding region through armed force.
Norbert Roettgen, head of the foreign affairs committee in the German parliament, was sceptical about how Russia would behave in the days and weeks ahead, despite agreeing to a cessation of hostilities.
"Russia is determined to create facts on the ground," Mr Roettgen said.
As the fighting continued, the Syrian army urged citizens in Deraa province, the Ghouta area east of Damascus, and in rural districts east of Aleppo to quickly seek out "reconciliation" with the government.
So-called local reconciliation agreements are often seen as a means for the government to force surrender on insurgents, and have typically followed lengthy blockades of rebel-held areas and the civilians living there.
Saudi Arabia confirmed it had sent aircraft to Turkey's Incirlik air base to join the fight against Islamic State. But said any move to deploy Saudi special forces into Syria would depend on a decision by the US-led coalition combating the ultra-radical militants.
US Defence Secretary Ash Carter said on Friday he expected Saudi Arabia and the United Arab Emirates to send special forces to Syria to help local opposition fighters in their drive to retake the city of Raqqa, Islamic State's de facto capital in Syria.