While he last played centre for the Raiders in the NRL in 2014, Wighton revealed he does train there for the Green Machine whenever co-captain Jarrod Croker needs a chopout.

NSW Blues coach Brad Fittler has backed Wighton to make the switch from the lime green No.6 to the Blues No.4 jersey.

Wighton's already made one stunning positional change this season, having transformed himself from Canberra's fullback to five-eighth.

Now he'll be called upon to try and stop Queensland's right centre-wing duo of Will Chambers and Dane Gagai.

Wighton has played 21 of his 143 NRL games in the centres, but the last of those was against St George Illawarra in round 23, 2014, before he made the Canberra fullback spot his own.

He was confident he could cope with the switch back.

"The week's been good. Just jumping back on the bike really, feeling comfortable and just excited to get back out there," Wighton said.

"[It's been] something like [five years]. I train there every now and then though.

"I always give Crokes a spell there at training so the muscle memory's there.

"I wouldn't be here if I wasn't full of confidence so I'm excited for the game."

Wighton's not the first Raider to make the switch from playing five-eighth in club land to return to the centres for the Blues.

Canberra legend Laurie Daley was basically wearing the Raiders No.6 jersey full-time from 1991 onwards.

He was playing the same position for the Blues from '92-94, before returning to the centres for NSW in 1996.

Fittler has called on Mark Gasnier's 12 Origins of experience to help Wighton and fellow Blues centre Tom Trbojevic adjust to their new roles, with Trbojevic also switching from his usual gig as Manly's fullback.

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Wighton didn't want to give too much away about what they'd been working on, slotting in on the Blues' left edge alongside winger Josh Addo-Carr.

"He's a legend mate. He's very well spoken, unreal footy knowledge as everybody knows," he said of Gasnier.

"He just understands football mate, he doesn't try and complicate things and that, so it's been really good.

"Nothing out of the blue mate. Just starting positions, just all the simple things, it's nothing too exciting.

"It's been good having him here that's for sure. I've enjoyed working with him and having a little chat.

"He's been great coming in that's for sure."

Wighton was excited about making his run-on debut, having come off the bench for the final 24 minutes of game one.

He'll go head to head with Chambers, who's known for his aggression and in-your-face antics.

Wighton said he would deal with that if and when it happened, but was only worried about himself.

"It's going to be a good one. That's what this game's all about. Just get out there and prove myself and be better than the opposition," he said.

"I'm really excited. Get in the game early, get a touch, get a tackle.

"As we all know that start of Origin games is a big blow out so get through that and then work with the boys."

Wighton acknowledged the Blues were under pressure, having lost game one to the Maroons 18-14, when Wighton's fellow Raider Josh Papalii was one of the stars for Queensland.

But he doesn't feel any additional pressure as a result of taking Latrell Mitchell's place in the Blues' line-up.

Mitchell was controversially overlooked because of his effort in Origin I, with Fittler opting for Wighton in his place.

The Raider backed Mitchell to return to the Blues XIII down the track.

"It's not about that mate. I've been given a job. I'm here to focus on me," Wighton said.

"I've been given a position. It's nothing personal, me and Latrell are boys, it's just how it works out sometimes.

"He's a freakish talent and at some stage he'll be back for sure. But I'm here to do a job this time."