Parts of the Australian National University were evacuated after a suspicious package was sent to the Chancelry building on Tuesday.
Multiple police officers, HAZMAT teams, and fire and rescue crews were called to the scene early in the afternoon.
Emergency crews began carrying out checks of the building to confirm if it was safe just after 1pm.
The Chancelry building is the location of university vice-chancellor Brian Schmidt's office.
A university spokesman said all staff were accounted for and safe in the building.
"At this point in time there is no indication that there is any immediate threat or danger to staff in the Chancelry or to the wider ANU campus and community," the spokesman said.
"The situation is contained.
"ANU is assisting emergency services with their ongoing investigation."
An ACT Policing spokeswoman said road closures were required as a result of the operation.
Upon investigation, police determined the suspicious package was not dangerous.
Staff were able to re-enter the building just before 4.30pm after the Chancelry was deemed safe by emergency authorities.