Josh Papalii, Jack Wighton and Josh Hodgson could all miss the game at Canberra Stadium on Saturday after being charged by the match review committee, with prop Papalii facing a five-week ban for his high tackle on Tuipolotu Katoa.

It also meant Papalii could miss Queensland's State of Origin opener at the MCG on June 9.

Wighton and Hodgson have been charged with grade-two dangerous contact, facing up to two weeks on the sideline for tackles on Adam Elliott and Luke Thompson respectively - downgraded to one week if they take the early guilty plea.

The Raiders will now consider whether they'll fight any of the charges at the judiciary.

They could welcome back Jordan Rapana (hamstring) and Ryan Sutton (elbow) from injury to face the Storm, while halves Sam Williams and Matt Frawley could be brought in for Wighton. Siliva Havili would be an option to replace Hodgson.

Papalii was the hardest hit for his high shot that saw him the first player sent off in the NRL's crackdown on high contact and foul play.

The crackdown has caused an uproar across the game, with NRL coaches Ricky Stuart, Trent Barrett and Todd Payten all critical of it.

Now Papalii's facing five weeks on the sideline for a grade-three careless high tackle - although that could be reduced to just three games with an early guilty plea.

It meant he could not only miss Origin I and the Storm, but the Raiders' round 12 meeting with the Sydney Roosters in Gosford as well.

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Some comfort for Canberra would be Storm stars Cameron Munster (foot) and Harry Grant (hamstring) could still be out due to injury.

Stuart had hoped Papalii's send-off - in the 61^st minute of the Green Machine's gutsy 20-18, come-from-behind victory against Canterbury on Saturday - would be the only punishment he'd receive.

But he could miss a massive chunk of the season if the Raiders fight the charge and lose.

Hodgson was charged for a chicken-wing tackle a minute after Papalii was sent off, while Wighton was charged for a cannonball tackle that also led to him being sin binned in the 54^th minute of the game.

It meant the Raiders were reduced to 11 players following Papalii's expulsion.

Bulldogs Sione Katoa and Ava Seumanufagai both escaped with fines for their dangerous contact charges - on Corey Harawira-Naera and Dunamis Lui respectively - of $1150 and $1700 with early guilty pleas.

Seumanufagai was lucky not to also find himself in the sin bin for his late hit on Lui.

NRL chief executive Andrew Abdo backed the crackdown and said whoever adapted the fastest would have an edge.

"What we know about our coaches and our teams is they're professional, they evolve, there's a learning curve and they'll adapt," he said on The Sunday Footy Show.

"And the teams that adapt quicker than others will have a competitive advantage."

NRL ROUND 11

Saturday: Canberra Raiders v Melbourne Storm at Canberra Stadium, 7.35pm.