The premier has faced considerable backlash over his management of the COVID-19 pandemic, including the imposition of mandatory vaccinations.

He confirmed on Wednesday he had indefinitely closed his electorate office in Rockingham, south of Perth, amid security concerns.

"There's been death threats, there's been threats to rape my staff, there's been people threatening to bomb my office," he told reporters.

"Someone turned up with an armoured car with a machine gun on the top. This is unbelievable conduct and so unfortunately that's what I've had to do.

"To target people's staff and their families is unfair. Unfortunately that's the way these people are conducting themselves, so I just ask them to stop and act like reasonable human beings."

Perth man Jamon Hartzer, 42, was last month charged over online threats to kill Premier Mark McGowan and other political leaders.

He was refused bail and will return to court next year.

Another man was charged days later with trying to firebomb a police station in Perth's south, allegedly motivated by WA's mandatory vaccination policy.

Gavin Michael Higgs faced court earlier this year accused of threatening to kill the premier outside his Rockingham home. He was convicted of disorderly conduct and placed under a community-based supervision order.

Mr McGowan's electorate office was also targeted during the March election campaign, with a man arrested over suspicious packages sent to the premier's office and that of federal Labor MP Madeleine King.

More recently, protesters have gathered outside Mr McGowan's home and bombarded him with calls and text messages after his personal phone number leaked.

The premier said he wouldn't be deterred from pursuing vaccine mandates amid hostile protests against coronavirus restrictions.

"We've seen it in Victoria, we're seeing it here, this sort of conduct which is threatening, intimidating, disgusting and disgraceful and they should stop, because it's not going to make the government change our policy," Mr McGowan said.

"We need to get people vaccinated."

Slightly higher than 70 per cent of West Australians aged 12 and over are fully vaccinated.

WA is looking to reopen its borders in late-January or early-February, subject to the state achieving a 90 per cent full vaccination rate.

Once the borders reopen, unvaccinated people - including West Australians - will be prevented from entering the state.

"If travelling domestically, unvaccinated persons, unless exempt or under 12 years, will not be permitted to enter WA unless they are vaccinated," senior government minister Sue Ellery told parliament under opposition questioning this week.

There are particular concerns around the low vaccination rate in remote areas, with just one in five Indigenous people fully vaccinated in the vast Pilbara region.

Australian Associated Press