Tszyu dominated Japanese rival Takeshi Inoue in Sydney on Wednesday night, winning every round on two of three scorecards in a fight that went the distance over 12 rounds.

Now the only thing standing in his way of a shot at WBO super welterweight champion Brian Castano is the dubious world of boxing politics.

Tszyu is the mandatory challenger for Castano but the Argentine may instead opt for a rematch against WBA, WBC and IBF champion Jermell Charlo after they battled to a stalemate in July.

There are plans for Tszyu to fight again in February or March, but whether or not a world title hangs in the balance remains to be seen.

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"The only murky waters here is the rematch," Tszyu's manager Glen Jennings said.

"Look, let's be honest, if those boys sat and watched what happened tonight, Tim doing 12 rounds like that, they're probably thinking it's an easier option to rematch than to take the mandates.

"We're expecting the IBF are going to make Charlo fight [Bakhram] Murtazaliev in January. If that happens, the WBO will most likely follow suit and say 'Castano, you now have to fight Tim'. That's what we're hoping for, and that should be pretty soon.

"We'll let No Limit deal with that and we just wait for the nod."

No Limit Boxing promoters George and Matt Rose now find themselves in the hot seat. As George puts it, a title clash with Tszyu is "a fight champions aren't going to want a bar of".

But they won't be able to run from the 20-0 Australian forever. Tszyu proved he is world class with a calculated demolition of Inoue. There is a sense of belief this is the fight Tszyu will look back at and know he needed it.

"I got used to these annihilations," Tszyu said.

"He was so durable, I just kept hitting him and he didn't go down. I heard him squealing. Usually when people squeal they go on the floor and they're squealing from the floor. This guy was squealing and staying up.

"If you're in the top five, 10, 15, of course it's going to be a challenge. There's no such thing as easy fights at this level."

No Limit staged an epic with 10,752 fans in the house in Homebush on Wednesday night. There is little doubt he would be able to pack out arenas time and time again on home soil, even if Tszyu's next bout is another to fill a void while he waits for a title shot.

"Castano is digging his heels in, he doesn't want to come to Australia, he wants it in America. We'd love to do another one here, we'd also like to do one in Las Vegas, so we'll see," Jennings said.

Las Vegas is boxing's heartbeat. It was the site of five bouts for Tim's legendary father Kostya Tszyu, with his devastating knockout of Zab Judah at the MGM Grand still spinning on highlight reels more than 20 years later.

"It's always been a dream of mine as a young kid growing up watching boxing on the big screen, to go to the States. I think it should be taken in the States and brought back here, the right way," Tszyu said.

"At the same time, it's pretty cool to be able to do it in front of 10,000 here in Sydney, especially for the fans. It's good to have all you guys covering everything here. It's great for Australian boxing and Australian sport in general to be doing shows here.

"Unreal man, unreal. I'm 27 years old and I'm pinching myself. To be able to walk out to 10,000 screaming fans all on my side, it's pretty crazy. Everything is happening so quick, it's pretty cool to be at this stage of my career."

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