Victoria has added 5046 new infections to its COVID-19 caseload along with a further four virus-related deaths.
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Health officials say the state is now managing just under 40,000 active coronavirus cases in total.
There are 219 virus patients in Victorian hospitals compared with 250 the previous day, while 27 of these are in intensive care units and seven are in need of ventilation.
Of the new infections, 3290 were detected using rapid antigen kits while 1756 came to light as a result of PCR lab tests.
Meanwhile, Victorians awaiting a third COVID-19 vaccine are being asked to donate blood to aid research.
Innovation and Medical Research Minister Jaala Pulford says the state's COVID-19 Vaccines Collection biobank, located at the Doherty Institute, is seeking up to 1500 blood donors to aid research.
The biobank will provide insight into the effectiveness of vaccines and the long-term effects of the virus, while also helping experts prepare for new strains.
Victorians due to receive their third dose are eligible, with donors providing blood samples over two years, including before and after receiving a third jab.
Ms Pulford says the elderly, people living with HIV, healthcare workers, people who've been infected with coronavirus and those who are immunocompromised are strongly encouraged to apply.
"This new biobank will be a key part of managing coronavirus going forward while allowing researchers to monitor the effects of vaccines and prepare for any new strains," she said on Saturday.
Some 60.5 per cent of Victorian adults have received three vaccine doses.
Australian Associated Press