The RSPCA will allege the 60-year-old was running a breeding operation purely to cash in on the popularity of the crossbreed with no concern for the dogs' welfare, health, and safety.

Inspectors went to the man's property, about 270 kilometres south of Perth, in January after receiving a cruelty report from a member of the public who had been to the house to buy a dog.

They reported finding filthy, squalid conditions reeking of urine and faeces.

The RSPCA alleged puppies were hiding in wet pools of urine while being stood on by the bigger dogs, some were lethargic, non-responsive and not exhibiting normal behaviour.

It said on examination by a vet, the dogs and puppies were found to be suffering from a variety of conditions including ear and other infections, conjunctivitis, embedded grass seeds, heavily matted fur, weight issues and dental disease.

The man has been charged over confining or restraining the dogs in a manner that causes or is likely to cause harm and with allowing the dogs to suffer harm which could be alleviated by the taking of reasonable steps.

He is due to appear in Manjimup Magistrates Court on June 16

The maximum penalty for each of the 28 animal cruelty charges is a $50,000 fine and five years in prison.

The seized dogs remain in the care of the RSPCA.

Australian Associated Press