A fourth person has died after a train carrying about 275 passengers and a dozen crew hit a dump truck at a railroad crossing and derailed.
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The victim was a passenger on the train, which was travelling from Los Angeles to Chicago on Monday when it collided with a dump truck near Mendon, Missouri, about 160 kilometres northeast of Kansas City, Missouri.
Two other passengers and the truck driver were also killed in the collision.
Eight cars and two locomotives derailed, rail company Amtrak officials said, leaving all but one car lying on its side along the track surrounded by grass and farmland.
Passengers escaped the wreck through windows facing skyward.
A Missouri State Highway Patrol spokesman said the collision occurred at an uncontrolled crossing without lights or signals.
About 150 people were transported from the scene to 10 area hospitals with injuries that ranged from minor to severe, the patrol said on Tuesday.
A team of 16 investigators from the US National Transportation Safety Board were on scene at the crash site Tuesday and launched an investigation.
Australian Associated Press