Isco Alarcon's debut was not enough to lift Sevilla to a first victory in the Spanish league as they remained winless after a 1-1 draw at home against Valladolid.
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The visitors took the lead with a goal by Anuar Mohamed in the 80th before Sevilla equalised through Karim Rekik in the 86th on Friday.
Isco, who arrived after his contract with Real Madrid was not renewed at the end of last season, came off the bench in the 68th minute but didn't do much to help the hosts.
Sevilla, who finished fourth in the league last season after staying near the top during most of the competition, opened this season's campaign with a 2-1 loss at Osasuna.
It was the team's first match since Mexico forward Jesus "Tecatito" Corona broke his leg in training in an injury that was likely to keep him from playing at the World Cup.
Valladolid, back in the first division after a one-year absence, opened their season with a 3-0 loss to Villarreal at home.
Rayo Vallecano followed up their draw against Barcelona at the Camp Nou with a 2-0 win at Espanyol, the other Barcelona city team.
Isi Palazon and Pathe Ciss scored a goal in each half for the visitors.
Both teams played most of the match with 10 men. Rayo lost Florian Lejeune to consecutive yellow cards two minutes apart in the 14th and 16th minutes while Espanyol lost defender Sergi Gomez to a straight red card in the 30th.
Espanyol had come from two goals down and scored late in stoppage time to open with a 2-2 draw at Celta Vigo.
Defending champions Real Madrid visit Celta on Saturday. On Sunday, Barcelona visit Real Sociedad while Atletico Madrid host Villarreal.
Australian Associated Press