Turner School parents were notified this week of four confirmed cases of whooping cough at the primary school so far this year.
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The school's newsletter issued a warning to parents saying the cases were discovered in the year 5/6 group of students and reminded parents to exclude their children from school for 21 days if they were infected.
The news comes after the ACT Health warned last week of a future outbreak of the disease in the territory.
ACT Health said that so far this year there have been 77 cases of whooping cough, or pertussis, confirmed and recorded in the territory.
"Whooping cough outbreaks are known to occur every three to four years, the most recent in the ACT was in 2010-2011/12," ACT Health said.
There were 712 cases of whooping cough reported in the ACT in 2010, and 829 in 2011.
The numbers of reported cases has steadied since then, with 234 cases reported in 2013 and 233 in 2014.
An ACT Health spokesman said the department was aware of the four confirmed cases at Turner School and had contacted the school, providing information on whooping cough for distribution to staff and parents.
The news comes two days after the ACT government launched an initiative offering free whooping cough vaccinations to pregnant women in the ACT in line with new research indicating it can help protect the baby after birth.
The spokesman said the whooping cough vaccine was administered under the National Immunisation Program to children aged two, four and six months of age, with boosters at four years of age and in year 7.
More than 92 per cent of Canberra children aged one and five years of age have been fully immunised under the program, with at least 93 per cent of children in these age groups receiving age-relevant vaccinations for whooping cough, according to the Australian Childhood Immunisation Register.
The spokesman said it was difficult to pinpoint the exact number of vaccinated ACT high school students because the register did not collect vaccination data for children older than seven years of age.
The ACT Health school health team and general practices administer the whooping cough vaccine to year 7 students.
"Based on data provided by the ACT Health school health team ... at least 70 per cent of high school students have been vaccinated," he said.
"The numbers of students immunised through general practice is unknown."
The spokesman said the whooping cough vaccine was recommended but not funded for other age groups.
He said older people were vaccinated at general practices via a private prescription.
"It is not known what the coverage rates are," he said.
"Immunity from the pertussis vaccine wanes over time. Therefore adults who were vaccinated as a child may not have any protection against the disease."
