A car and a motorcycle collided outside Campbell High School and the Australian War Memorial on Limestone Avenue on Thursday afternoon.
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An Emergency Services Agency spokesman said the male motorcyclist was semi-conscious and sustained a head injury.
He was treated by paramedics on scene and taken to the Canberra Hospital in a stable condition.
Emergency services were called to the scene about 12.10pm.
An ACT Policing spokeswoman said the crash had closed Limestone Avenue's eastbound lanes.
The road was re-opened as of 1pm.
Cars were originally diverted down Ainslie Avenue and traffic had banked up in the area.