Activists in Mexico are urging women to avoid going out, going to work or school, or going shopping on Monday, to draw attention to the number of women taken from the community by violence.
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The protest has generated widespread public debate on the streets of Mexico about the symbolism of becoming "invisible" for a day.
A Facebook group called "A Day Without Women" has more than 320,000 Mexican members.
A message to the group says a woman staying indoors on Monday is meant to "simulate" her death - to show those close to her what would happen if she were to suddenly disappear or die at the hands of a man, like the thousands who are killed each year in Mexico.
Government data say 3,825 women met violent deaths last year, 7 per cent more than in 2018. That works out to about 10 women slain each day in Mexico, making it one of the most dangerous countries in the world for females. Thousands more have gone missing without a trace in recent years.
In Mexico, major banks, media companies and law firms have joined the call to action. The Coparmex business confederation encouraged its more than 36,000 member companies across the country to take part.
Some private schools have cancelled bus services that depend on female nannies to walk children to their front doors, and some enlisted fathers of schoolchildren to give classes in the absence of female teachers.
It appears public hospitals and schools that heavily depend on female personnel will open, perhaps with fewer employees on hand.
President Andres Manuel Lopez Obrador at first accused conservative political opponents of being behind the strike as a way to criticise his government. But he later invited federal employees, including men, to participate, promising no reprisals.
Not all women support the action. Some say it is pointless or part of a feminist agenda that seeks to legalise abortion throughout the Roman Catholic country.
Millions of Mexican women with precarious employment can't afford to lose a day's pay, much less their jobs, and don't have male partners to take on childcare duties for a day.
Australian Associated Press