Health Minister Rachel Stephen-Smith said the ACT lacked the infrastructure to make hosting repatriation flights and mandatory hotel quarantine cost effective.

"We have made the decision not to take any further repatriation flights at this point in time. Part of the reason for that is it is a very expensive process for us," Ms Stephen-Smith said.

She told ABC radio on Wednesday the ACT had decided not to take anymore flights after larger centres were again hosting Australians returning from overseas.

"With Melbourne reopening, a lot more people can be accommodated through the major international airports than our repatriation flight facility," Ms Stephen-Smith said.

"It really is a very significant logistical excercise, it's quite expensive because we just don't have those economies of scale in doing that work.

"And so from a cost-benefit perspective, it just seemed more sensible to pay our share of ACT residents coming in through other capital cities."

The ACT had taken five repatriation flights, with passengers forced into quarantine at the Pacific Suites hotel on Northbourne Avenue.

Ms Stephen-Smith had previously said the territory would welcome more repatriation flights in 2021.

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Earlier the territory government said it only had capacity to take one flight every two weeks, as it requires quarantine hotel rooms to have a kitchenette and balcony.

The Pacific Suites hotel is the only one suitable hotel which has signed up to take part.

Meanwhile, Ms Stephen-Smith confirmed the Calvary vaccination hub, which would only administer the AstraZeneca jab, would open on May 3.

The government has revised down the hub's expected capacity, after the size of the hub was overestimated.

Calvary was expected to deliver 1700 vaccinations a week, but Ms Stephen-Smith said it would be closer to 680 a week with room to expand.

"It's partly around demand, it's partly around the space that's available. There was a bit of an overestimation of what we could deliver in that space," she said.

From May 3, the Garran Surge Centre would only administer the Pfizer vaccine. The site has so far delivered about 22,000 vaccinations.

Ms Stephen-Smith said the ACT government was not administering the AstraZeneca vaccine to people under 50, in line with advice from the Therapeutic Goods Administration, but younger people could talk to their doctor about the potential risk before if they were willing to take the vaccine.

"We know now that we have a good supply of AstraZeneca, but we need to be getting it out through general practitioners," she said.

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