Police said an argument broke out between two men about 3pm on Saturday at the Upper Coomera centre.

The ute driver left in his vehicle before allegedly returning and deliberately crashing into the van containing three men.

It will be further alleged a passenger got out of the van and stabbed the passenger of the ute in the upper arm.

The alleged stabbing victim fled the scene before police arrived and was later found at the Gold Coast University Hospital.

A second passenger of the van was taken to Gold Coast University Hospital with a foot injury.

A 19-year-old Coomera man has been charged with wounding and going armed so as to cause fear.

A 33-year-old Upper Coomera man was charged with dangerous operation of a vehicle.

Both men will appear in Southport Magistrates Court on Monday.

Detective Inspector Brendan Smith said there were no public safety concerns after the incident.

"Both men are known to each other with police investigating the circumstances surrounding the dispute," he said.

“Behaviour, such as seen today, will not be tolerated and the Queensland Police Service will bring all available resources to bear to bring offenders before the courts.”

Investigations are continuing.

Witnesses are encouraged to contact Policelink on 131 444.